Play and motor development in inbred strains and selected lines of Mus musculus

Play and motor development in inbred strains and selected lines of Mus musculus by Maria Jacoba Lavooy Download PDF EPUB FB2

Differences in the number of chromosomes with secondary constrictions and in the size of the C-band region on certain chromosomes have been observed among the following inbred strains of Mus musculus: C57BL/10J, C57BR/cdJ, DBA/1J, CBA/J, BALB/cJ, and differences are useful as indicators of the location of rRNA genes and as normal chromosome by:   These results suggest that otolithic function varies among inbred strains and several strains displayed gravity receptor deficits by 90 days old.

Auditory brainstem response (ABR) thresholds were compared to VsEP thresholds for 14 age-matched by:   The reproduction of Eimeria vermiformis in different strains of phenotypically normal mice and in mice with various immunological characteristics or defects was compared.

In some strains of phenotypically normal mice there were marked differences in oocyst production, both in terms of numbers and in the duration of patency, allowing the strains to be classified as resistant or susceptible to Cited by:   Metten P, Crabbe JC () Alcohol withdrawal severity in inbred mouse (Mus musculus) strains.

Behav Neurosci – PubMed Google Scholar Metten P, Belknap JK, Crabbe JC () Drug withdrawal convulsions and susceptibility to convulsants after short-term selective breeding for acute ethanol by: Quiet mutations in inbred strains of mice. preceding the development of the first inbred strain (DBA), from a Mus musculus domesticus source.

As GPR84 ostensibly plays a role in the biology of. Historically, gene targeting was first done in embryonic stem cells (ESCs) derived from the family of inbred strains, leading to a mixed background or congenic mice when crossed with C57BL/6 mice.

The hybrid sterility 1 (Hst1) gene was originally described in male progeny obtained from a cross between laboratory inbred mouse strains C57BL/10 and C3H, and wild Mus musculus musculus. The present study compared olfactory discrimination learning in CD-1 mice, a widely used outbred strain of mice with that of C57BL/6J mice, one of the most widely used inbred mouse strains.

Dose level and frequency were selected based on prior pharmacokinetic and pharmacodynamic studies (Patel et al., ; Le Pichon et al., ).

To first verify the inhibitor compound indeed reduced DLK signaling in DRG neurons, we examined gene expression of Atf3 and Csf1 at 5 dpi in L4 DRGs in GNE versus vehicle-treated mice. Start studying Motor Development Exam 4. Learn vocabulary, terms, and more with flashcards, games, and other study tools.

Artificial selection was carried out to develop lines of mice that would show High (HRT) and Low (LRT) levels of Rapid Tolerance. Starting with HS/Npt mice, derived from a systematic cross of eight inbred strains, a significant response to selection was seen in replicate 1 by the third selection generation.

No difference was found in replicate 2. Motor Development Chapter STUDY. Flashcards. Learn. Write. Spell. Test. PLAY. Match. Gravity. Created by. mmarti2. Haywood. Terms in this set (34) Psychosocial Influences _____ _____ are described as an "interaction of individual functional constraints.

As discussed earlier in this chapter and previous ones, the traditional inbred M. musculus strains show minimal levels of interstrain polymorphism. It was for this reason that the initial two-generation mapping panels were all based on interspecific crosses between a M.

musculus strain and a M. spretus strain as described in Section   More than genetically defined inbred strains are available from several centers worldwide.

Although most classical inbred strains are genomic mosaics descending from several mouse (sub)species, a growing list of wild-derived inbred strains have pure, species-specific origin. Wild-derived inbred strains are available from Mus musculus domesticus, Mus musculus musculus, Mus musculus molossinus, Mus musculus castaneus, Mus spretus, and Mus.

Download Citation | Insights into mammalian biology from the wild house mouse Mus musculus | The house mouse, Mus musculus, was established in the early s as one of the first genetic model. The first inbred strain (formed by repeated brother–sister mating) was the DBA, called after the three recessively inherited alleles: dilution (d), brown (b) and nonagouti (a) which characterized it.

However, Castle was unpersuaded about the value of breeding ‘pure strains’ of animals and, after army service in the First World War, Little. Email your librarian or administrator to recommend adding this book to your organisation's collection.

F., et al. () Hippocampal gene expression profiling across eight mouse inbred strains: towards understanding the molecular basis actions in male mouse lines selected for aggressive and nonaggressive behavior. Genes Brain Behav 3. Mus musculus (L) is the polytypic species which encompasses all the subspecies and geographical or chromosomal races of the house mouse.

It is also the species which has paid the largest tribute to modern science, since the historical laboratory strains (the ‘old inbreds’) stem from this species through the old tradition of ‘fancy’ mice which were bred in Europe and Asia for their coat color.

RECOMBINANT INBRED STRAINS Overview Conceptualization and history of RI strains. Although a handful of isolated recombinant inbred (RI) mouse strains were developed during the s and s, the importance of these genetic constructs was not appreciated by any scientist prior to Dr.

Donald Bailey who first conceptualized their potential utility for linkage analysis while. For two inbred strains, /Rr and BALB/cGn, the midpoint of ovulation was to hours after the midpoint of the dark period in a 7-hours-dark to hours-light cycle (Whitten and Dagg, ).

Some of the apparent discrepancies in earlier reports may have been due to using mating time rather than the light-dark cycle as a reference point.

Start studying Motor development test 2. Learn vocabulary, terms, and more with flashcards, games, and other study tools.8. Olfactory acuity in Mus musculus H. Schellinck and B. Slotnick 9. Taste genetics J. Boughter Part III. Autonomous and Motor Behaviors Motor coordination in inbred mouse strains and the crucial role of the cerebellum R.

Lalonde and C. Strazielle Reflex development F. Cirulli and E. Alleva The Mus musculus domesticus strains (Zalende/EiJ, WSB/EiJ and PERA/EiJ) cluster together near the lower end of the phenotypic range while the five wild-derived strains with a predominantly Mus musculus musculus background (Yang et al.

) cluster at the higher end of the phenotypic range. Interestingly, subspecific clustering was not observed for rearing behavior.